Disease: Neurodevelopmental Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ARHGEF9 O43307 Cdc42 guanine nucleotide exchange factor 9 Enzyme modulator 1.00 0.691 0.385
WDR62 O43379 WD repeat domain 62 2.4E-23 0.597 0.615
KCNQ2 O43526 potassium voltage-gated channel subfamily Q member 2 Ion channel 1.00 0.537 0.654
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
ZNF292 O60281 zinc finger protein 292 Enzyme 1.00 0.695 0.423
BRINP1 O60477 BMP/retinoic acid inducible neural specific 1 0.99 0.615 0.615
GREM1 O60565 gremlin 1, DAN family BMP antagonist 0.47 0.508 0.808
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
ASTN2 O75129 astrotactin 2 1.00 0.666 0.462
DEAF1 O75398 DEAF1 transcription factor 3.4E-04 0.575 0.615
TRIO O75962 trio Rho guanine nucleotide exchange factor Kinase 1.00 0.556 0.731
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
CNTN5 O94779 contactin 5 6.2E-05 0.695 0.462
ATG7 O95352 autophagy related 7 Enzyme 7.4E-12 0.505 0.769
SLU7 O95391 SLU7 homolog, splicing factor Nucleic acid binding 1.6E-09 0.729 0.346
HERC2 O95714 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.00 0.568 0.692
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
OPN1LW P04000 opsin 1, long wave sensitive G-protein coupled receptor 0.98 0.497 0.808
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
HMGN1 P05114 high mobility group nucleosome binding domain 1 Nucleic acid binding 0.21 0.711 0.538