Disease: Hormone refractory prostate cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CFLAR O15519 CASP8 and FADD like apoptosis regulator Enzyme 1.00 0.485 0.846
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885