Disease: PACHYONYCHIA CONGENITA 3
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
GHRH P01286 growth hormone releasing hormone Signaling 0.15 0.503 0.769
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
GRP P07492 gastrin releasing peptide 2.5E-03 0.524 0.769
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
LONP1 P36776 lon peptidase 1, mitochondrial Enzyme 1.00 0.517 0.808
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923