Disease: Ambiguous Genitalia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769
AMH P03971 anti-Mullerian hormone 3.4E-12 0.476 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
DHRS11 Q6UWP2 dehydrogenase/reductase 11 Enzyme 2.2E-06 0.653 0.423
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
HSD17B13 Q7Z5P4 hydroxysteroid 17-beta dehydrogenase 13 2.7E-05 0.623 0.538
HSD17B3 P37058 hydroxysteroid 17-beta dehydrogenase 3 8.5E-07 0.641 0.346
HSD17B7 P56937 hydroxysteroid 17-beta dehydrogenase 7 6.6E-06 0.582 0.500
HSD3B2 P26439 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Enzyme 7.2E-08 0.582 0.500
IRF6 O14896 interferon regulatory factor 6 Transcription factor 1.00 0.486 0.769
LHCGR P22888 luteinizing hormone/choriogonadotropin receptor G-protein coupled receptor 5.3E-08 0.528 0.692
MAP3K1 Q13233 mitogen-activated protein kinase kinase kinase 1 Kinase 1.00 0.538 0.731
MYRF Q9Y2G1 myelin regulatory factor 1.00 0.584 0.731
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
SRD5A2 P31213 steroid 5 alpha-reductase 2 Enzyme 0.564 0.615
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
ZFY P08048 zinc finger protein Y-linked Transcription factor 0.69 0.716 0.308