Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
RASSF10 | A6NK89 | Ras association domain family member 10 | 0.626 | 0.385 | ||
IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
LATS1 | O95835 | large tumor suppressor kinase 1 | Kinase | 1.00 | 0.563 | 0.731 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
MMP3 | P08254 | matrix metallopeptidase 3 | Enzyme | 5.7E-15 | 0.408 | 0.885 |
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
HGF | P14210 | hepatocyte growth factor | Enzyme | 1.00 | 0.374 | 0.885 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
MT3 | P25713 | metallothionein 3 | 6.4E-02 | 0.582 | 0.615 | |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
MT1X | P80297 | metallothionein 1X | 9.3E-04 | 0.619 | 0.692 | |
NOTCH2 | Q04721 | notch receptor 2 | 1.00 | 0.441 | 0.808 | |
TLE2 | Q04725 | TLE family member 2, transcriptional corepressor | Transcription factor | 1.6E-07 | 0.805 | 0.192 |
ACVR1 | Q04771 | activin A receptor type 1 | Kinase | 0.33 | 0.535 | 0.731 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
NTRK2 | Q16620 | neurotrophic receptor tyrosine kinase 2 | Kinase | 1.00 | 0.479 | 0.808 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MCOLN2 | Q8IZK6 | mucolipin 2 | Ion channel | 1.3E-14 | 0.805 | 0.192 |