Disease: Keratoderma, Palmoplantar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COL17A1 Q9UMD9 collagen type XVII alpha 1 chain 2.3E-27 0.545 0.769
CTC1 Q2NKJ3 CST telomere replication complex component 1 1.6E-11 0.601 0.538
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
FLNA P21333 filamin A 1.00 0.419 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
ITGB4 P16144 integrin subunit beta 4 Receptor 9.5E-19 0.525 0.731
KRT14 P02533 keratin 14 2.0E-04 0.530 0.731
KRT17 Q04695 keratin 17 1.1E-11 0.531 0.654
KRT5 P13647 keratin 5 0.64 0.512 0.731
KRT83 P78385 keratin 83 3.4E-14 0.716 0.269
LAMA3 Q16787 laminin subunit alpha 3 Enzyme modulator 8.8E-46 0.576 0.731
LAMB3 Q13751 laminin subunit beta 3 Enzyme modulator 2.3E-15 0.558 0.692
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
NHP2 Q9NX24 NHP2 ribonucleoprotein Nucleic acid binding 5.0E-02 0.623 0.654
NOP10 Q9NPE3 NOP10 ribonucleoprotein Nucleic acid binding 0.77 0.631 0.654
RIPK4 P57078 receptor interacting serine/threonine kinase 4 Kinase 4.0E-03 0.565 0.654
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TINF2 Q9BSI4 TERF1 interacting nuclear factor 2 1.3E-03 0.575 0.731
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TRPV3 Q8NET8 transient receptor potential cation channel subfamily V member 3 Ion channel 4.6E-20 0.610 0.577
WNT10A Q9GZT5 Wnt family member 10A Signaling 4.2E-09 0.547 0.731
WRAP53 Q9BUR4 WD repeat containing antisense to TP53 5.4E-05 0.603 0.692