Disease: Joint hyperflexibility
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC6 O95255 ATP binding cassette subfamily C member 6 Transporter 5.6E-35 0.540 0.654
ANTXR1 Q9H6X2 ANTXR cell adhesion molecule 1 Receptor 0.99 0.584 0.731
ARID2 Q68CP9 AT-rich interaction domain 2 1.00 0.543 0.808
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CDC45 O75419 cell division cycle 45 Nucleic acid binding 4.6E-05 0.588 0.692
CDC6 Q99741 cell division cycle 6 1.1E-09 0.552 0.731
CDT1 Q9H211 chromatin licensing and DNA replication factor 1 2.6E-10 0.597 0.731
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
COL5A1 P20908 collagen type V alpha 1 chain 1.00 0.536 0.769
COL5A2 P05997 collagen type V alpha 2 chain 1.00 0.568 0.731
CRKL P46109 CRK like proto-oncogene, adaptor protein 0.45 0.553 0.769
ELN P15502 elastin 2.1E-14 0.415 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808
IFT122 Q9HBG6 intraflagellar transport 122 2.4E-24 0.560 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
NFIX Q14938 nuclear factor I X Nucleic acid binding 1.00 0.547 0.769
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
ORC1 Q13415 origin recognition complex subunit 1 Nucleic acid binding 1.7E-14 0.595 0.654