Disease: Keratoderma, Palmoplantar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA12 Q86UK0 ATP binding cassette subfamily A member 12 Transporter 2.9E-15 0.610 0.654
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
ALOXE3 Q9BYJ1 arachidonate lipoxygenase 3 Enzyme 5.1E-20 0.644 0.538
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CTC1 Q2NKJ3 CST telomere replication complex component 1 1.6E-11 0.601 0.538
DKC1 O60832 dyskerin pseudouridine synthase 1 Nucleic acid binding 1.00 0.547 0.769
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
MAP2K2 P36507 mitogen-activated protein kinase kinase 2 Kinase 0.97 0.534 0.731
NHP2 Q9NX24 NHP2 ribonucleoprotein Nucleic acid binding 5.0E-02 0.623 0.654
NIPAL4 Q0D2K0 NIPA like domain containing 4 1.4E-03 0.682 0.423
NOP10 Q9NPE3 NOP10 ribonucleoprotein Nucleic acid binding 0.77 0.631 0.654
PARN O95453 poly(A)-specific ribonuclease Nucleic acid binding 3.7E-04 0.575 0.769
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
TERC telomerase RNA component 0.471 0.846
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TGM1 P22735 transglutaminase 1 Enzyme 2.3E-13 0.565 0.769
TINF2 Q9BSI4 TERF1 interacting nuclear factor 2 1.3E-03 0.575 0.731
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
USB1 Q9BQ65 U6 snRNA biogenesis phosphodiesterase 1 6.9E-04 0.636 0.577
WNT10A Q9GZT5 Wnt family member 10A Signaling 4.2E-09 0.547 0.731