Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
SUFU | Q9UMX1 | SUFU negative regulator of hedgehog signaling | 1.00 | 0.493 | 0.769 | |
RYR1 | P21817 | ryanodine receptor 1 | Ion channel | 1.6E-29 | 0.489 | 0.808 |
TCF4 | P15884 | transcription factor 4 | Transcription factor | 1.00 | 0.464 | 0.846 |
TPM2 | P07951 | tropomyosin 2 | Cellular structure | 2.4E-04 | 0.530 | 0.654 |
PIGN | O95427 | phosphatidylinositol glycan anchor biosynthesis class N | Extracellular structure | 2.3E-21 | 0.558 | 0.615 |
ACTA1 | P68133 | actin alpha 1, skeletal muscle | Cellular structure | 1.1E-06 | 0.540 | 0.769 |
RAI1 | Q7Z5J4 | retinoic acid induced 1 | Transcription factor | 1.00 | 0.545 | 0.731 |
GPC4 | O75487 | glypican 4 | 0.93 | 0.547 | 0.769 | |
PIGL | Q9Y2B2 | phosphatidylinositol glycan anchor biosynthesis class L | 6.2E-09 | 0.581 | 0.731 | |
HUWE1 | Q7Z6Z7 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 | Enzyme | 1.00 | 0.534 | 0.769 |
ROR2 | Q01974 | receptor tyrosine kinase like orphan receptor 2 | Kinase | 1.2E-04 | 0.498 | 0.731 |
IQSEC2 | Q5JU85 | IQ motif and Sec7 domain ArfGEF 2 | 1.00 | 0.573 | 0.577 | |
CDKL5 | O76039 | cyclin dependent kinase like 5 | Kinase | 1.00 | 0.522 | 0.692 |
FAT4 | Q6V0I7 | FAT atypical cadherin 4 | 1.00 | 0.539 | 0.808 | |
TPM3 | P06753 | tropomyosin 3 | Cellular structure | 6.7E-03 | 0.490 | 0.808 |
DEAF1 | O75398 | DEAF1 transcription factor | 3.4E-04 | 0.575 | 0.615 | |
KMT2D | O14686 | lysine methyltransferase 2D | 1.00 | 0.465 | 0.808 | |
SELENON | Q9NZV5 | selenoprotein N | 9.8E-10 | 0.575 | 0.692 | |
UBA5 | Q9GZZ9 | ubiquitin like modifier activating enzyme 5 | Enzyme | 2.5E-04 | 0.582 | 0.731 |
FOXG1 | P55316 | forkhead box G1 | 0.94 | 0.522 | 0.692 |