Disease: PACHYONYCHIA CONGENITA 3
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
TACSTD2 P09758 tumor associated calcium signal transducer 2 4.7E-03 0.537 0.731
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
MIR200B microRNA 200b 0.500 0.769
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885