Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
STS P08842 steroid sulfatase Enzyme 0.81 0.431 0.846
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
PNKP Q96T60 polynucleotide kinase 3'-phosphatase 3.7E-14 0.553 0.692
TOP1 P11387 DNA topoisomerase I Enzyme 1.00 0.542 0.692
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
APTX Q7Z2E3 aprataxin Nucleic acid binding 4.0E-10 0.590 0.500
XRCC6P5 X-ray repair cross complementing 6 pseudogene 5 0.579 0.769
NRF1 Q16656 nuclear respiratory factor 1 1.00 0.603 0.808