Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
NFE2L2 | Q16236 | nuclear factor, erythroid 2 like 2 | Enzyme | 3.6E-03 | 0.357 | 0.885 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
GABPA | Q06546 | GA binding protein transcription factor subunit alpha | Transcription factor | 1.00 | 0.379 | 0.885 |
PARP1 | P09874 | poly(ADP-ribose) polymerase 1 | 3.3E-04 | 0.389 | 0.923 | |
MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
XRCC1 | P18887 | X-ray repair cross complementing 1 | 6.3E-09 | 0.421 | 0.923 | |
IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
STS | P08842 | steroid sulfatase | Enzyme | 0.81 | 0.431 | 0.846 |
OGG1 | O15527 | 8-oxoguanine DNA glycosylase | 3.9E-12 | 0.453 | 0.808 | |
APEX1 | P27695 | apurinic/apyrimidinic endodeoxyribonuclease 1 | 1.9E-07 | 0.458 | 0.846 | |
SDHA | P31040 | succinate dehydrogenase complex flavoprotein subunit A | Enzyme | 2.6E-10 | 0.517 | 0.731 |
FXN | Q16595 | frataxin | Enzyme | 0.34 | 0.510 | 0.654 |
MRE11 | P49959 | MRE11 homolog, double strand break repair nuclease | 1.3E-12 | 0.527 | 0.808 | |
PNKP | Q96T60 | polynucleotide kinase 3'-phosphatase | 3.7E-14 | 0.553 | 0.692 | |
TOP1 | P11387 | DNA topoisomerase I | Enzyme | 1.00 | 0.542 | 0.692 |
SETX | Q7Z333 | senataxin | Enzyme | 0.95 | 0.570 | 0.731 |
APTX | Q7Z2E3 | aprataxin | Nucleic acid binding | 4.0E-10 | 0.590 | 0.500 |
XRCC6P5 | X-ray repair cross complementing 6 pseudogene 5 | 0.579 | 0.769 | |||
NRF1 | Q16656 | nuclear respiratory factor 1 | 1.00 | 0.603 | 0.808 |