Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
TUBB P07437 tubulin beta class I Cellular structure 0.98 0.603 0.692
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CHN1 P15882 chimerin 1 3.1E-02 0.573 0.615
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
GNA11 P29992 G protein subunit alpha 11 Enzyme modulator 0.89 0.563 0.731
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808