Disease: Factor V Leiden mutation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADAMTS13 Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 5.1E-15 0.496 0.769
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ATD asphixiating thoracic dystrophy (chondroectodermal dysplasia-like syndrome) 0.656 0.731
C20orf181 chromosome 20 open reading frame 181 0.479 0.885
CHRM3 P20309 cholinergic receptor muscarinic 3 G-protein coupled receptor 0.99 0.464 0.885
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
CPB2 Q96IY4 carboxypeptidase B2 Enzyme 2.7E-17 0.536 0.846
CYP2C9 P11712 cytochrome P450 family 2 subfamily C member 9 1.3E-10 0.506 0.885
DHFR P00374 dihydrofolate reductase Enzyme 3.4E-02 0.513 0.808
F10 P00742 coagulation factor X Enzyme 2.3E-06 0.493 0.769
F13A1 P00488 coagulation factor XIII A chain Enzyme 5.3E-08 0.575 0.731
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
F8 P00451 coagulation factor VIII Enzyme 1.00 0.542 0.769
F9 P00740 coagulation factor IX Enzyme 1.00 0.465 0.885
FGB P02675 fibrinogen beta chain Signaling 0.57 0.584 0.692
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
GPI P06744 glucose-6-phosphate isomerase Enzyme 2.8E-06 0.491 0.769
HABP2 Q14520 hyaluronan binding protein 2 Enzyme 2.0E-15 0.593 0.615
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885