Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808
FKTN O75072 fukutin 8.7E-07 0.511 0.692
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846