Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
PIK3CD | O00329 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Kinase | 1.00 | 0.319 | 0.885 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
PIK3CB | P42338 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | Kinase | 1.00 | 0.322 | 0.885 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
CCR5 | P51681 | C-C motif chemokine receptor 5 (gene/pseudogene) | G-protein coupled receptor | 4.3E-10 | 0.398 | 0.885 |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
BRD4 | O60885 | bromodomain containing 4 | Epigenetic regulator | 1.00 | 0.446 | 0.885 |
RASA1 | P20936 | RAS p21 protein activator 1 | Enzyme modulator | 1.00 | 0.481 | 0.885 |
AKT3 | Q9Y243 | AKT serine/threonine kinase 3 | Kinase | 1.00 | 0.512 | 0.808 |
MMUT | P22033 | methylmalonyl-CoA mutase | Enzyme | 1.7E-22 | 0.534 | 0.731 |
SYNGAP1 | Q96PV0 | synaptic Ras GTPase activating protein 1 | Enzyme modulator | 1.00 | 0.584 | 0.577 |
PIK3R2 | O00459 | phosphoinositide-3-kinase regulatory subunit 2 | Enzyme modulator | 1.6E-02 | 0.551 | 0.808 |
CDC45 | O75419 | cell division cycle 45 | Nucleic acid binding | 4.6E-05 | 0.588 | 0.692 |
MCM10 | Q7L590 | minichromosome maintenance 10 replication initiation factor | 4.4E-15 | 0.691 | 0.462 |