Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TUBB2A Q13885 tubulin beta 2A class IIa Cellular structure 0.93 0.678 0.538
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808