Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
PLG | P00747 | plasminogen | Enzyme | 1.0E-02 | 0.389 | 0.923 |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
CDKN2B | P42772 | cyclin dependent kinase inhibitor 2B | 7.3E-03 | 0.417 | 0.769 | |
FLT1 | P17948 | fms related receptor tyrosine kinase 1 | Kinase | 1.00 | 0.419 | 0.846 |
CFTR | P13569 | CF transmembrane conductance regulator | Ion channel | 2.2E-58 | 0.424 | 0.885 |
PECAM1 | P16284 | platelet and endothelial cell adhesion molecule 1 | Cell adhesion | 0.426 | 0.846 | |
ABO | P16442 | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | Enzyme | 0.427 | 0.885 | |
LPA | P08519 | lipoprotein(a) | Enzyme | 6.6E-89 | 0.444 | 0.769 |
LOX | P28300 | lysyl oxidase | 0.99 | 0.447 | 0.846 | |
LDLR | P01130 | low density lipoprotein receptor | 9.8E-24 | 0.449 | 0.885 | |
SMARCA4 | P51532 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | Epigenetic regulator | 1.00 | 0.450 | 0.885 |
TEK | Q02763 | TEK receptor tyrosine kinase | Kinase | 1.00 | 0.462 | 0.692 |
ABCA1 | O95477 | ATP binding cassette subfamily A member 1 | Transporter | 1.5E-13 | 0.467 | 0.846 |
IL6R | P08887 | interleukin 6 receptor | Signaling | 3.2E-05 | 0.471 | 0.846 |
ZEB2 | O60315 | zinc finger E-box binding homeobox 2 | Transcription factor | 1.00 | 0.471 | 0.808 |
LPL | P06858 | lipoprotein lipase | Enzyme | 1.3E-09 | 0.474 | 0.808 |
HNF1A | P20823 | HNF1 homeobox A | Nucleic acid binding | 0.96 | 0.478 | 0.846 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |