Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ABCA7 | Q8IZY2 | ATP binding cassette subfamily A member 7 | Transporter | 2.1E-55 | 0.644 | 0.577 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CHCHD10 | Q8WYQ3 | coiled-coil-helix-coiled-coil-helix domain containing 10 | 5.4E-06 | 0.623 | 0.462 | |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
SORL1 | Q92673 | sortilin related receptor 1 | Transporter | 7.7E-11 | 0.582 | 0.692 |
SPAST | Q9UBP0 | spastin | Cellular structure | 1.00 | 0.579 | 0.577 |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
TOMM40 | O96008 | translocase of outer mitochondrial membrane 40 | Transporter | 0.99 | 0.590 | 0.538 |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 |