Disease: Advanced breast cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IL2 P60568 interleukin 2 0.48 0.336 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
MIR155 microRNA 155 0.384 0.885
MIR200B microRNA 200b 0.500 0.769
MIR21 microRNA 21 0.363 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
RRM2B Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 2.4E-03 0.527 0.769
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962