Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
DCC P43146 DCC netrin 1 receptor 0.99 0.471 0.808
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
SCN9A Q15858 sodium voltage-gated channel alpha subunit 9 Ion channel 4.8E-19 0.543 0.615