Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
CA9 | Q16790 | carbonic anhydrase 9 | 1.3E-09 | 0.483 | 0.731 | |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
LEPR | P48357 | leptin receptor | Signaling | 0.99 | 0.433 | 0.808 |
LOX | P28300 | lysyl oxidase | 0.99 | 0.447 | 0.846 | |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
MT1A | P04731 | metallothionein 1A | 4.5E-03 | 0.537 | 0.808 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PON1 | P27169 | paraoxonase 1 | 9.8E-11 | 0.409 | 0.885 | |
PTK2B | Q14289 | protein tyrosine kinase 2 beta | Kinase | 0.94 | 0.448 | 0.808 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
USF2 | Q15853 | upstream transcription factor 2, c-fos interacting | 0.99 | 0.626 | 0.654 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |