Disease: Severe intellectual disability
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADGRG1 Q9Y653 adhesion G protein-coupled receptor G1 G-protein coupled receptor 5.3E-10 0.590 0.654
ADNP Q9H2P0 activity dependent neuroprotector homeobox 1.00 0.561 0.808
ANKLE2 Q86XL3 ankyrin repeat and LEM domain containing 2 1.0E-10 0.691 0.500
AP1S2 P56377 adaptor related protein complex 1 subunit sigma 2 Transporter 0.87 0.631 0.615
AP4B1 Q9Y6B7 adaptor related protein complex 4 subunit beta 1 Transporter 1.3E-09 0.631 0.654
AP4E1 Q9UPM8 adaptor related protein complex 4 subunit epsilon 1 Receptor 2.8E-03 0.656 0.385
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
ASPM Q8IZT6 abnormal spindle microtubule assembly 3.4E-49 0.526 0.769
ATP1A1 P05023 ATPase Na+/K+ transporting subunit alpha 1 Transporter 1.00 0.601 0.808
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
C12orf57 Q99622 chromosome 12 open reading frame 57 5.2E-05 0.641 0.500
CDK5RAP2 Q96SN8 CDK5 regulatory subunit associated protein 2 4.6E-23 0.682 0.577
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
CENPJ Q9HC77 centromere protein J Enzyme 2.1E-27 0.546 0.846
CEP135 Q66GS9 centrosomal protein 135 Enzyme modulator 3.6E-22 0.695 0.615
CEP152 O94986 centrosomal protein 152 Signaling 2.7E-27 0.653 0.500
CEP63 Q96MT8 centrosomal protein 63 Cellular structure 6.2E-25 0.666 0.500
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
CIT O14578 citron rho-interacting serine/threonine kinase Kinase 1.00 0.555 0.692
CLCN4 P51793 chloride voltage-gated channel 4 Ion channel 1.00 0.587 0.654
CNNM2 Q9H8M5 cyclin and CBS domain divalent metal cation transport mediator 2 1.00 0.641 0.346
COPB2 P35606 COPI coat complex subunit beta 2 Transporter 1.00 0.644 0.615