Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |
NF2 | P35240 | neurofibromin 2 | 1.00 | 0.468 | 0.885 | |
DICER1 | Q9UPY3 | dicer 1, ribonuclease III | Enzyme | 1.00 | 0.446 | 0.846 |
BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
FH | P07954 | fumarate hydratase | Enzyme | 8.8E-02 | 0.489 | 0.846 |
MRE11 | P49959 | MRE11 homolog, double strand break repair nuclease | 1.3E-12 | 0.527 | 0.808 | |
ETV5 | P41161 | ETS variant transcription factor 5 | Transcription factor | 1.00 | 0.565 | 0.731 |
POT1 | Q9NUX5 | protection of telomeres 1 | Nucleic acid binding | 0.85 | 0.560 | 0.731 |
KIAA1549 | Q9HCM3 | KIAA1549 | 0.99 | 0.615 | 0.346 |