Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
JAK2 | O60674 | Janus kinase 2 | Kinase | 0.65 | 0.385 | 0.885 |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
S100B | P04271 | S100 calcium binding protein B | Calcium-binding protein | 4.4E-02 | 0.383 | 0.923 |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
RPE65 | Q16518 | retinoid isomerohydrolase RPE65 | Enzyme | 6.5E-14 | 0.417 | 0.808 |
BMP4 | P12644 | bone morphogenetic protein 4 | Signaling | 0.96 | 0.422 | 0.808 |
GLI3 | P10071 | GLI family zinc finger 3 | 1.00 | 0.436 | 0.846 | |
S100A1 | P23297 | S100 calcium binding protein A1 | Calcium-binding protein | 6.0E-03 | 0.421 | 0.846 |
DKK1 | O94907 | dickkopf WNT signaling pathway inhibitor 1 | 0.17 | 0.439 | 0.885 | |
GLI1 | P08151 | GLI family zinc finger 1 | 7.7E-14 | 0.431 | 0.846 | |
GLI2 | P10070 | GLI family zinc finger 2 | 0.97 | 0.446 | 0.846 | |
MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 |
UVRAG | Q9P2Y5 | UV radiation resistance associated | 0.99 | 0.436 | 0.769 | |
CKAP4 | Q07065 | cytoskeleton associated protein 4 | 0.51 | 0.436 | 0.731 | |
RTEL1 | Q9NZ71 | regulator of telomere elongation helicase 1 | Enzyme | 8.9E-10 | 0.459 | 0.808 |