Disease: Adult type dermatomyositis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WG Wegener granulomatosis 0.595 0.808
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
ELANE P08246 elastase, neutrophil expressed Enzyme 1.2E-03 0.447 0.846
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962
ACR P10323 acrosin Enzyme 1.2E-02 0.493 0.846
CD28 P10747 CD28 molecule 0.36 0.436 0.885
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923