Disease: Familial multiple trichoepitheliomata
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCN1 O00622 cellular communication network factor 1 Signaling 0.71 0.473 0.731
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
COMMD3-BMI1 P35226 COMMD3-BMI1 readthrough 1.5E-03 0.488 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
MAP1LC3B Q9GZQ8 microtubule associated protein 1 light chain 3 beta Cellular structure 1.9E-03 0.506 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846