Disease: Muscle Spasticity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769
NEFL P07196 neurofilament light 0.488 0.769
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
RTTN Q86VV8 rotatin 9.0E-34 0.619 0.654
RPGRIP1L Q68CZ1 RPGRIP1 like Enzyme modulator 4.1E-31 0.534 0.769
PRSS12 P56730 serine protease 12 Enzyme 8.4E-29 0.682 0.308
CC2D2A Q9P2K1 coiled-coil and C2 domain containing 2A 1.7E-27 0.532 0.692
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
SACS Q9NZJ4 sacsin molecular chaperone 1.1E-23 0.606 0.654
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769
POLR3B Q9NW08 RNA polymerase III subunit B Enzyme 1.7E-23 0.628 0.654
KIF7 Q2M1P5 kinesin family member 7 2.3E-22 0.528 0.731
MAN2B1 O00754 mannosidase alpha class 2B member 1 4.8E-22 0.674 0.462
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
PIGN O95427 phosphatidylinositol glycan anchor biosynthesis class N Extracellular structure 2.3E-21 0.558 0.615
POMGNT1 Q8WZA1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.9E-20 0.537 0.538
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
SPATA5 Q8NB90 spermatogenesis associated 5 9.1E-20 0.670 0.654
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731