Disease: Primary Progressive Aphasia (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BPIFA2 Q96DR5 BPI fold containing family A member 2 8.0E-07 0.608 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
FOXP2 O15409 forkhead box P2 1.00 0.545 0.808
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
NEFL P07196 neurofilament light 0.488 0.769
PPA1 Q15181 inorganic pyrophosphatase 1 Enzyme 1.9E-05 0.656 0.615
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PSPH P78330 phosphoserine phosphatase Enzyme 9.7E-04 0.570 0.808
PSPN O60542 persephin Signaling 1.1E-04 0.608 0.769
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
RIDA P52758 reactive intermediate imine deaminase A homolog 6.8E-02 0.606 0.769
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
STXBP3 O00186 syntaxin binding protein 3 Transporter 5.2E-05 0.610 0.769
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
VCP P55072 valosin containing protein 1.00 0.469 0.923