Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
ENG P17813 endoglin 1.00 0.446 0.846
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
BEST1 O76090 bestrophin 1 Ion channel 1.8E-12 0.465 0.885
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
VCAN P13611 versican Extracellular structure 1.00 0.497 0.808
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
THPO P40225 thrombopoietin 0.20 0.513 0.692
RHO P08100 rhodopsin G-protein coupled receptor 1.3E-04 0.525 0.769
ADA2 Q9NZK5 adenosine deaminase 2 Enzyme 8.1E-08 0.545 0.846
PRPH2 P23942 peripherin 2 0.12 0.551 0.500
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692