Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
JAK2 | O60674 | Janus kinase 2 | Kinase | 0.65 | 0.385 | 0.885 |
TWIST1 | Q15672 | twist family bHLH transcription factor 1 | Transcription factor | 0.34 | 0.397 | 0.846 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
ENG | P17813 | endoglin | 1.00 | 0.446 | 0.846 | |
EPCAM | P16422 | epithelial cell adhesion molecule | 1.3E-07 | 0.451 | 0.885 | |
COL3A1 | P02461 | collagen type III alpha 1 chain | 1.00 | 0.477 | 0.808 | |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
BEST1 | O76090 | bestrophin 1 | Ion channel | 1.8E-12 | 0.465 | 0.885 |
COL4A1 | P02462 | collagen type IV alpha 1 chain | 1.00 | 0.484 | 0.731 | |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
MPL | P40238 | MPL proto-oncogene, thrombopoietin receptor | Receptor | 4.1E-09 | 0.510 | 0.692 |
FXN | Q16595 | frataxin | Enzyme | 0.34 | 0.510 | 0.654 |
VCAN | P13611 | versican | Extracellular structure | 1.00 | 0.497 | 0.808 |
BMPR1A | P36894 | bone morphogenetic protein receptor type 1A | Kinase | 0.90 | 0.522 | 0.731 |
THPO | P40225 | thrombopoietin | 0.20 | 0.513 | 0.692 | |
RHO | P08100 | rhodopsin | G-protein coupled receptor | 1.3E-04 | 0.525 | 0.769 |
ADA2 | Q9NZK5 | adenosine deaminase 2 | Enzyme | 8.1E-08 | 0.545 | 0.846 |
PRPH2 | P23942 | peripherin 2 | 0.12 | 0.551 | 0.500 | |
SEMA4A | Q9H3S1 | semaphorin 4A | Signaling | 1.8E-05 | 0.569 | 0.692 |