Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
SLC6A4 | P31645 | solute carrier family 6 member 4 | Transporter | 0.25 | 0.429 | 0.808 |
CHI3L1 | P36222 | chitinase 3 like 1 | 1.1E-05 | 0.419 | 0.885 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
NEFL | P07196 | neurofilament light | 0.488 | 0.769 | ||
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
IGFALS | P35858 | insulin like growth factor binding protein acid labile subunit | Receptor | 5.4E-11 | 0.511 | 0.846 |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
RUNX1T1 | Q06455 | RUNX1 partner transcriptional co-repressor 1 | Transcription factor | 0.98 | 0.530 | 0.808 |
SLC25A20 | O43772 | solute carrier family 25 member 20 | Transporter | 1.2E-07 | 0.563 | 0.769 |
TMEM106B | Q9NUM4 | transmembrane protein 106B | 0.33 | 0.590 | 0.462 |