Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
FLNB O75369 filamin B 6.1E-10 0.458 0.923
EBP Q15125 EBP cholestenol delta-isomerase Enzyme 0.94 0.494 0.846
CTSK P43235 cathepsin K Enzyme 3.1E-05 0.497 0.808
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846
COMP P49747 cartilage oligomeric matrix protein 1.3E-09 0.503 0.808
CA2 P00918 carbonic anhydrase 2 1.7E-06 0.506 0.808
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731
LONP1 P36776 lon peptidase 1, mitochondrial Enzyme 1.00 0.517 0.808
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
RMRP RNA component of mitochondrial RNA processing endoribonuclease 0.519 0.731
SMARCA2 P51531 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Epigenetic regulator 1.00 0.527 0.769
KIF7 Q2M1P5 kinesin family member 7 2.3E-22 0.528 0.731
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846