| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
| AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
| FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
| SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
| IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
| IDH2 | P48735 | isocitrate dehydrogenase (NADP(+)) 2 | 0.88 | 0.434 | 0.808 | |
| VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |
| ENG | P17813 | endoglin | 1.00 | 0.446 | 0.846 | |
| TEK | Q02763 | TEK receptor tyrosine kinase | Kinase | 1.00 | 0.462 | 0.692 |
| ACVRL1 | P37023 | activin A receptor like type 1 | Kinase | 9.7E-04 | 0.493 | 0.769 |
| GNAQ | P50148 | G protein subunit alpha q | Enzyme modulator | 0.98 | 0.516 | 0.808 |
| SLC26A2 | P50443 | solute carrier family 26 member 2 | Transporter | 7.5E-07 | 0.553 | 0.692 |
| PTH1R | Q03431 | parathyroid hormone 1 receptor | G-protein coupled receptor | 0.57 | 0.544 | 0.731 |
| GDF2 | Q9UK05 | growth differentiation factor 2 | Signaling | 2.5E-03 | 0.529 | 0.731 |