Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
SMARCB1 | Q12824 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | Nucleic acid binding | 1.00 | 0.434 | 0.846 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
ABCC8 | Q09428 | ATP binding cassette subfamily C member 8 | Transporter | 8.0E-24 | 0.474 | 0.846 |
NF2 | P35240 | neurofibromin 2 | 1.00 | 0.468 | 0.885 | |
PDGFB | P01127 | platelet derived growth factor subunit B | Signaling | 0.77 | 0.488 | 0.846 |
SUFU | Q9UMX1 | SUFU negative regulator of hedgehog signaling | 1.00 | 0.493 | 0.769 | |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
KCNJ11 | Q14654 | potassium inwardly rectifying channel subfamily J member 11 | Ion channel | 1.1E-02 | 0.529 | 0.615 |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
COQ2 | Q96H96 | coenzyme Q2, polyprenyltransferase | Enzyme | 1.3E-03 | 0.590 | 0.731 |
TMEM106B | Q9NUM4 | transmembrane protein 106B | 0.33 | 0.590 | 0.462 | |
SLC6A1 | P30531 | solute carrier family 6 member 1 | Transporter | 1.00 | 0.592 | 0.538 |
CHD2 | O14647 | chromodomain helicase DNA binding protein 2 | 1.00 | 0.585 | 0.577 |