Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HNRNPA1 P09651 heterogeneous nuclear ribonucleoprotein A1 1.00 0.529 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
KEAP1 Q14145 kelch like ECH associated protein 1 3.9E-04 0.475 0.808
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFL P07196 neurofilament light 0.488 0.769
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSAP P07602 prosaposin 0.99 0.532 0.846
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SYNCRIP O60506 synaptotagmin binding cytoplasmic RNA interacting protein Nucleic acid binding 1.00 0.722 0.269