Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
NFE2L2 | Q16236 | nuclear factor, erythroid 2 like 2 | Enzyme | 3.6E-03 | 0.357 | 0.885 |
CXCR4 | P61073 | C-X-C motif chemokine receptor 4 | G-protein coupled receptor | 1.8E-02 | 0.362 | 0.923 |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
CFTR | P13569 | CF transmembrane conductance regulator | Ion channel | 2.2E-58 | 0.424 | 0.885 |
MS4A1 | P11836 | membrane spanning 4-domains A1 | Receptor | 5.1E-05 | 0.411 | 0.846 |
CD19 | P15391 | CD19 molecule | 0.90 | 0.430 | 0.885 | |
TFRC | P02786 | transferrin receptor | Enzyme | 7.0E-05 | 0.437 | 0.885 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
RTEL1 | Q9NZ71 | regulator of telomere elongation helicase 1 | Enzyme | 8.9E-10 | 0.459 | 0.808 |
XIAP | P98170 | X-linked inhibitor of apoptosis | Enzyme modulator | 0.92 | 0.447 | 0.808 |
IL21 | Q9HBE4 | interleukin 21 | 0.63 | 0.441 | 0.769 | |
DNMT3B | Q9UBC3 | DNA methyltransferase 3 beta | 0.20 | 0.453 | 0.846 | |
LIG4 | P49917 | DNA ligase 4 | 4.2E-06 | 0.478 | 0.846 | |
BTK | Q06187 | Bruton tyrosine kinase | Kinase | 1.00 | 0.464 | 0.808 |
PRKCD | Q05655 | protein kinase C delta | Kinase | 1.00 | 0.480 | 0.846 |
PIK3R1 | P27986 | phosphoinositide-3-kinase regulatory subunit 1 | Kinase | 1.00 | 0.477 | 0.885 |
TNFRSF11A | Q9Y6Q6 | TNF receptor superfamily member 11a | 8.8E-03 | 0.480 | 0.846 | |
DCTN4 | Q9UJW0 | dynactin subunit 4 | 0.73 | 0.472 | 0.846 |