Disease: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACR P10323 acrosin Enzyme 1.2E-02 0.493 0.846
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
PRTN3 P24158 proteinase 3 Enzyme 3.8E-05 0.503 0.808
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
SERPINA13P Q6UXR4 serpin family A member 13, pseudogene 0.619 0.692
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
WG Wegener granulomatosis 0.595 0.808