Disease: Nail abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AAGAB Q6PD74 alpha and gamma adaptin binding protein 3.9E-07 0.695 0.538
ABCA12 Q86UK0 ATP binding cassette subfamily A member 12 Transporter 2.9E-15 0.610 0.654
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
ALOXE3 Q9BYJ1 arachidonate lipoxygenase 3 Enzyme 5.1E-20 0.644 0.538
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CERS3 Q8IU89 ceramide synthase 3 5.7E-03 0.705 0.308
COL14A1 Q05707 collagen type XIV alpha 1 chain Receptor 1.4E-14 0.674 0.615
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
DSG1 Q02413 desmoglein 1 Cell adhesion 0.93 0.606 0.538
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462
GJB4 Q9NTQ9 gap junction protein beta 4 Cell-cell junction 5.5E-04 0.691 0.462
KDSR Q06136 3-ketodihydrosphingosine reductase 0.12 0.674 0.538
KRT1 P04264 keratin 1 0.74 0.575 0.654
KRT14 P02533 keratin 14 2.0E-04 0.530 0.731
KRT5 P13647 keratin 5 0.64 0.512 0.731
KRT6A P02538 keratin 6A 7.0E-05 0.610 0.692
KRT6B P04259 keratin 6B 5.5E-10 0.663 0.577
KRT83 P78385 keratin 83 3.4E-14 0.716 0.269
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
NIPAL4 Q0D2K0 NIPA like domain containing 4 1.4E-03 0.682 0.423
PKP1 Q13835 plakophilin 1 Cellular structure 5.8E-04 0.659 0.462