Disease: Progressive intrahepatic cholestasis (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCB11 O95342 ATP binding cassette subfamily B member 11 Transporter 1.6E-12 0.566 0.654
ABCB4 P21439 ATP binding cassette subfamily B member 4 Transporter 2.2E-07 0.529 0.615
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
ABCC4 O15439 ATP binding cassette subfamily C member 4 Transporter 1.1E-07 0.536 0.769
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ATP8B1 O43520 ATPase phospholipid transporting 8B1 Transporter 2.8E-10 0.610 0.500
DNAH8 Q96JB1 dynein axonemal heavy chain 8 Enzyme 1.1E-60 0.556 0.731
FGF19 O95750 fibroblast growth factor 19 Signaling 0.57 0.548 0.615
GGT1 P19440 gamma-glutamyltransferase 1 Enzyme 7.5E-05 0.496 0.885
GGT2 P36268 gamma-glutamyltransferase 2 1.3E-04 0.513 0.846
GGTLC1 Q9BX51 gamma-glutamyltransferase light chain 1 Enzyme 3.3E-05 0.559 0.731
GGTLC3 B5MD39 gamma-glutamyltransferase light chain family member 3 0.513 0.846
GGTLC4P gamma-glutamyltransferase light chain 4 pseudogene 0.513 0.846
GGTLC5P gamma-glutamyltransferase light chain 5 pseudogene 0.513 0.846
HSD3B7 Q9H2F3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Enzyme 2.7E-08 0.700 0.385
IMMT Q16891 inner membrane mitochondrial protein 1.3E-02 0.576 0.846
KLHL1 Q9NR64 kelch like family member 1 7.2E-07 0.569 0.654
LOC102724197 inactive glutathione hydrolase 2 0.559 0.731
MYO5B Q9ULV0 myosin VB Cellular structure 3.4E-23 0.641 0.731
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808
SLC10A2 Q12908 solute carrier family 10 member 2 Transporter 9.6E-17 0.621 0.538
SLC25A13 Q9UJS0 solute carrier family 25 member 13 Transporter 1.3E-24 0.617 0.500