Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
PRKAR1A | P10644 | protein kinase cAMP-dependent type I regulatory subunit alpha | 1.00 | 0.401 | 0.846 | |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
PON1 | P27169 | paraoxonase 1 | 9.8E-11 | 0.409 | 0.885 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
HNF4A | P41235 | hepatocyte nuclear factor 4 alpha | Nuclear receptor | 0.15 | 0.461 | 0.808 |
CACNA1A | O00555 | calcium voltage-gated channel subunit alpha1 A | Ion channel | 1.00 | 0.489 | 0.769 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
ABCC8 | Q09428 | ATP binding cassette subfamily C member 8 | Transporter | 8.0E-24 | 0.474 | 0.846 |
ERBB4 | Q15303 | erb-b2 receptor tyrosine kinase 4 | Kinase | 1.00 | 0.455 | 0.846 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
HNF1A | P20823 | HNF1 homeobox A | Nucleic acid binding | 0.96 | 0.478 | 0.846 |
UCHL1 | P09936 | ubiquitin C-terminal hydrolase L1 | Enzyme | 0.99 | 0.482 | 0.885 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
TSHR | P16473 | thyroid stimulating hormone receptor | G-protein coupled receptor | 3.0E-15 | 0.486 | 0.808 |
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 |