Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846
PROS1 P07225 protein S 4.7E-04 0.467 0.846
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
RASA1 P20936 RAS p21 protein activator 1 Enzyme modulator 1.00 0.481 0.885
PLAG1 Q6DJT9 PLAG1 zinc finger Transcription factor 1.00 0.493 0.808
KLF6 Q99612 Kruppel like factor 6 Nucleic acid binding 0.98 0.501 0.846
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
AMACR Q9UHK6 alpha-methylacyl-CoA racemase 2.7E-02 0.510 0.769
PPM1D O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 2.2E-11 0.513 0.808
NPEPPS P55786 aminopeptidase puromycin sensitive Enzyme 1.00 0.519 0.808
RASA2 Q15283 RAS p21 protein activator 2 Enzyme modulator 7.4E-31 0.579 0.769
PKHD1 P08F94 PKHD1 ciliary IPT domain containing fibrocystin/polyductin 1.2E-47 0.576 0.654
MSR1 P21757 macrophage scavenger receptor 1 Enzyme 2.2E-20 0.553 0.654