Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
ALB | P02768 | albumin | Transporter | 0.64 | 0.317 | 0.962 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
MMP3 | P08254 | matrix metallopeptidase 3 | Enzyme | 5.7E-15 | 0.408 | 0.885 |
TNFRSF11B | O00300 | TNF receptor superfamily member 11b | 0.16 | 0.422 | 0.808 | |
NOTCH3 | Q9UM47 | notch receptor 3 | 0.41 | 0.435 | 0.808 | |
KLK3 | P07288 | kallikrein related peptidase 3 | Enzyme | 4.4E-06 | 0.443 | 0.885 |
SPARC | P09486 | secreted protein acidic and cysteine rich | Signaling | 0.89 | 0.445 | 0.846 |
MMP13 | P45452 | matrix metallopeptidase 13 | Enzyme | 7.9E-18 | 0.452 | 0.923 |
TNFSF11 | O14788 | TNF superfamily member 11 | Signaling | 4.9E-03 | 0.453 | 0.846 |
SDC1 | P18827 | syndecan 1 | Extracellular structure | 8.4E-03 | 0.445 | 0.769 |
FOLH1 | Q04609 | folate hydrolase 1 | Enzyme | 6.2E-09 | 0.453 | 0.885 |
MAOA | P21397 | monoamine oxidase A | 1.00 | 0.465 | 0.769 | |
PSAT1 | Q9Y617 | phosphoserine aminotransferase 1 | 1.1E-08 | 0.478 | 0.846 | |
PROS1 | P07225 | protein S | 4.7E-04 | 0.467 | 0.846 | |
TYR | P14679 | tyrosinase | Enzyme | 5.0E-32 | 0.473 | 0.808 |
PLAG1 | Q6DJT9 | PLAG1 zinc finger | Transcription factor | 1.00 | 0.493 | 0.808 |
MC1R | Q01726 | melanocortin 1 receptor | G-protein coupled receptor | 8.1E-11 | 0.524 | 0.808 |