Gene: TREM2 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs150277350
rs150277350
TREM2 ; TREML1 ; LOC105375056
0.010 GeneticVariation BEFREE Together these data provide evidence that the A192T variant in TREM2 could contribute risk for AD. 28376694

2017
dbSNP: rs149622783
rs149622783
TREM2 ; TREML1 ; LOC105375056
0.010 GeneticVariation BEFREE In addition, we identified rare variant R136Q in a patient with language-predominant AD that also showed impaired surface expression. 27589997

2016
dbSNP: rs201280312
rs201280312
TREM2 ; LOC105375056
0.010 GeneticVariation BEFREE As a result, none of these 3 variants were identified in all subjects, however, 1 novel variant (p.A130V) in TREM2 and 4 novel variants (p.Q860H, p.T837K, p.S843G, and p.V836V) in UNC5C were detected in unrelated patients with late-onset AD. 24866402

2014