DisGeNET - a database of gene-disease associations

Alzheimer's Disease, C0002395

Variant: rs1880676 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1880676

CHAT

0.030

GeneticVariation

BEFREE

Association of Choline Acetyltransferase Gene Polymorphisms (SNPs rs868750G/A, rs1880676G/A, rs2177369G/A and rs3810950G/A) with Alzheimer's Disease Risk: A Meta-Analysis.

27390868

2016

dbSNP:

rs1880676

CHAT

0.030

GeneticVariation

BEFREE

No association was detected between rs1880676 and rs868750 and AD</span> risk.

27272392

2016

dbSNP:

rs1880676

CHAT

0.030

GeneticVariation

BEFREE

Furthermore, an association of rs1880676 with AD was specific to carriers of the APOEε4 risk allele (p = 0.008, genotype; OR = 3.47 95% CI 1.50-8.01 p = 0.005 allele-wise).

21507424

2011