Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE BDNF Val66Met polymorphism is associated with higher anticipatory cortisol stress response, anxiety, and alcohol consumption in healthy adults. 21596481

2011

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Assuming that BDNF may be implicated in the putative common pathophysiology of depression and anxiety, we analyzed the association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (formerly named C270T) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with panic disorder. 15913870

2005

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE Association of COMT (Val158Met) and BDNF (Val66Met) gene polymorphisms with anxiety, ADHD and tics in children with autism spectrum disorder. 19582565

2009

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE A polymorphism of the human Brain Derived Neurotrophic Factor (BDNF) gene that produces a valine-to-methionine substitution at codon 66 (Val66Met) is linked to adult anxiety and mood disorders, possibly through effects on brain circuitry function. 19931400

2010

dbSNP: rs759834365
rs759834365
0.100 GeneticVariation BEFREE A common polymorphism of the brain-derived neurotrophic factor (BDNF) gene (Val66Met) has been implicated in anxiety, which is associated with lower vagal activity. 20213725

2010