DisGeNET - a database of gene-disease associations

Rheumatoid Arthritis, C0003873

Variant: rs11568821 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs11568821

PDCD1 ; LOC105373977

0.030

GeneticVariation

BEFREE

This study aims to analyze the relationship of programmed cell death 1 (PDCD1) gene polymorphism (PD1.3G/A - rs11568821) with features of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) in a Southern Brazilian population.

27914594

2018

dbSNP:

rs11568821

PDCD1 ; LOC105373977

0.030

GeneticVariation

BEFREE

The present study suggests that mutant A allele in rs11568821 (PD-1.3 G/A) might increase the susceptibility to RA in Caucasians.

28858091

2017

dbSNP:

rs11568821

PDCD1 ; LOC105373977

0.030

GeneticVariation

BEFREE

Previous investigations have also demonstrated that an intronic polymorphism (termed PD1.3; SNP ID rs11568821) in the programmed cell death (PDCD1) gene was associated with systemic lupus erythematosus and rheumatoid arthritis.

17535987

2007