Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801394
rs1801394
MTRR ; FASTKD3
0.070 GeneticVariation BEFREE SHMT C1420T mutations may reduce breast cancer susceptibility, whereas MTRR A66G and MS A2756G mutations may increase breast cancer susceptibility. 27347936

2016
dbSNP: rs1801394
rs1801394
MTRR ; FASTKD3
0.070 GeneticVariation BEFREE Cross-talk was observed between one-carbon and xenobiotic pathways in breast cancer (RFC 80 G>A, COMT H108L and TYMS 5'-UTR 28 bp tandem repeat) and SLE (CYP1A1 m1, MTRR 66 A>G and GSTT1). 25648260

2015
dbSNP: rs1801394
rs1801394
MTRR ; FASTKD3
0.070 GeneticVariation BEFREE Our findings suggested that MTRR A66G polymorphism was not associated with breast cancer susceptibility. 24815481

2014
dbSNP: rs1801394
rs1801394
MTRR ; FASTKD3
0.070 GeneticVariation BEFREE MTRR A66G and cSHMT C1420T polymorphisms influence CIMP phenotype of BNIP3, thus epigenetically regulating BNIP3 in breast cancer. 21987236

2012
dbSNP: rs1801394
rs1801394
MTRR ; FASTKD3
0.070 GeneticVariation BEFREE In conclusion, this meta-analysis strongly suggests that MTRR A66G polymorphism is not associated with breast cancer risk, especially in Caucasians and Asians. 20411324

2010
dbSNP: rs1801394
rs1801394
MTRR ; FASTKD3
0.070 GeneticVariation BEFREE In addition, interaction between the MTRR A66G polymorphism and folate intake for risk of postmenopausal breast cancer was observed (interaction P = 0.008). 18174236

2008
dbSNP: rs1801394
rs1801394
MTRR ; FASTKD3
0.070 GeneticVariation BEFREE Viable cell growth, MDI, and polymorphism frequency in MTRR (A66G and C524T) and MTHFR (A1298C and A1793G) did not differ among the study groups; however, MDI tended to be higher in BRCA carriers with breast cancer than those without and was significantly increased in MTHFR 677T allele carriers relative to wild-type carriers (P=0.017). 18842997

2008