Gene: PIK3CA ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913281
rs121913281
PIK3CA
T 0.700 CausalMutation CLINVAR

dbSNP: rs121913283
rs121913283
PIK3CA
A 0.700 GeneticVariation CLINVAR

dbSNP: rs397517200
rs397517200
PIK3CA
A 0.700 GeneticVariation CLINVAR

dbSNP: rs397517202
rs397517202
PIK3CA
G 0.700 CausalMutation CLINVAR

dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR A novel dual PI3Kalpha/mTOR inhibitor PI-103 with high antitumor activity in non-small cell lung cancer cells. 19513541

2009
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR A novel dual PI3Kalpha/mTOR inhibitor PI-103 with high antitumor activity in non-small cell lung cancer cells. 19513541

2009
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR A novel dual PI3Kalpha/mTOR inhibitor PI-103 with high antitumor activity in non-small cell lung cancer cells. 19513541

2009
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR A novel dual PI3Kalpha/mTOR inhibitor PI-103 with high antitumor activity in non-small cell lung cancer cells. 19513541

2009
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR A novel dual PI3Kalpha/mTOR inhibitor PI-103 with high antitumor activity in non-small cell lung cancer cells. 19513541

2009
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. 16906227

2006
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
dbSNP: rs104886003
rs104886003
PIK3CA
A 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs121913273
rs121913273
PIK3CA
A 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs121913279
rs121913279
PIK3CA
G 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs121913279
rs121913279
PIK3CA
T 0.700 CausalMutation CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981

2008
dbSNP: rs104886003
rs104886003
PIK3CA
C 0.700 CausalMutation CLINVAR Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. 21430269

2011