rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The missense point mutation BRAF(V600E) was identified in 42% (13/31 cases) of papillary carcinomas and 33% (5/15 cases) of undifferentiated carcinomas but not in normal thyroid tissues, nodular hyperplasia, follicular adenomas, or follicular carcinomas.
|
17714762 |
2007 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Next generation sequencing showed BRAF V600E mutation in the primary papillary carcinoma and NRAS Q61R mutation in the primary follicular carcinoma and bony metastasis.
|
28710706 |
2018 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
All three papillary carcinomas accompanied by anaplastic carcinoma with a BRAF V600E mutation were also shown to have a BRAF V600E mutation.</span>
|
17453004 |
2007 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Given the strong genotype:phenotype correlation known to be present in thyroid cancer, the separation of BRAF(V600E)-like and RAS-like tumors has profound implications for its classification, especially the follicular variant of papillary carcinoma.
|
26569424 |
2016 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Common molecular alterations, such as BRAF p.V600E, RAS point mutations, and fusion oncogenes (RET-PTC being the prototypical example), have been, respectively, associated with conventional papillary carcinoma, follicular-patterned tumours (follicular adenoma, follicular carcinoma, and the follicular variant of papillary carcinoma/non-invasive follicular thyroid neoplasm with papillary-like nuclear features), and with papillary carcinomas from young patients and arising after exposure to ionising radiation, respectively.
|
29239040 |
2018 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These findings indicate that, although BRAF(V600E) mutation may play some roles in local carcinoma development, there is no evidence that BRAF(V600E) mutation significantly reflects the aggressive characteristics and poor prognosis of patients with papillary carcinoma in Japan.
|
18840924 |
2009 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BRAF V600E mutation and p27 kip1 expression in papillary carcinomas of the thyroid <or=1 cm and their paired lymph node metastases.
|
17685465 |
2007 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BRAF V600E mutation was detected in 68 % (71/104) of papillary carcinoma cases and 78 % (7/9) of anaplastic carcinoma cases.
|
25894433 |
2015 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The T1799A BRAF mutation is absent in cribriform-morular variant of papillary carcinoma.
|
19415957 |
2009 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A high percentage of both melanomas and papillary carcinomas of the thyroid harbors a recurrent mutation (i.e., BRAF(V600E) ) in the BRAF oncogene.
|
24574369 |
2014 |
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: a meta-analysis.
|
17520704 |
2007 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BRAF V600E mutation was detected in 68 % (71/104) of papillary carcinoma cases and 78 % (7/9) of anaplastic carcinoma cases.
|
25894433 |
2015 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: a meta-analysis.
|
17520704 |
2007 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
All three papillary carcinomas accompanied by anaplastic carcinoma with a BRAF V600E mutation were also shown to have a BRAF V600E mutation.</span>
|
17453004 |
2007 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Given the strong genotype:phenotype correlation known to be present in thyroid cancer, the separation of BRAF(V600E)-like and RAS-like tumors has profound implications for its classification, especially the follicular variant of papillary carcinoma.
|
26569424 |
2016 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Next generation sequencing showed BRAF V600E mutation in the primary papillary carcinoma and NRAS Q61R mutation in the primary follicular carcinoma and bony metastasis.
|
28710706 |
2018 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These findings indicate that, although BRAF(V600E) mutation may play some roles in local carcinoma development, there is no evidence that BRAF(V600E) mutation significantly reflects the aggressive characteristics and poor prognosis of patients with papillary carcinoma in Japan.
|
18840924 |
2009 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Common molecular alterations, such as BRAF p.V600E, RAS point mutations, and fusion oncogenes (RET-PTC being the prototypical example), have been, respectively, associated with conventional papillary carcinoma, follicular-patterned tumours (follicular adenoma, follicular carcinoma, and the follicular variant of papillary carcinoma/non-invasive follicular thyroid neoplasm with papillary-like nuclear features), and with papillary carcinomas from young patients and arising after exposure to ionising radiation, respectively.
|
29239040 |
2018 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The missense point mutation BRAF(V600E) was identified in 42% (13/31 cases) of papillary carcinomas and 33% (5/15 cases) of undifferentiated carcinomas but not in normal thyroid tissues, nodular hyperplasia, follicular adenomas, or follicular carcinomas.
|
17714762 |
2007 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BRAF V600E mutation and p27 kip1 expression in papillary carcinomas of the thyroid <or=1 cm and their paired lymph node metastases.
|
17685465 |
2007 |
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A high percentage of both melanomas and papillary carcinomas of the thyroid harbors a recurrent mutation (i.e., BRAF(V600E) ) in the BRAF oncogene.
|
24574369 |
2014 |
rs121913364
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The c.1801A>G mutation was identified in 4 follicular variant papillary carcinomas and one follicular carcinoma.
|
25120313 |
2014 |
rs121913529
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A KRAS G12V mutation was detected in the plasma of 1 patient with stage IVA papillary carcinoma whose tissue contained the same mutation.
|
29498908 |
2018 |
rs1057519695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Next generation sequencing showed BRAF V600E mutation in the primary papillary carcinoma and NRAS Q61R mutation in the primary follicular carcinoma and bony metastasis.
|
28710706 |
2018 |
rs1057519834
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Next generation sequencing showed BRAF V600E mutation in the primary papillary carcinoma and NRAS Q61R mutation in the primary follicular carcinoma and bony metastasis.
|
28710706 |
2018 |