We conducted a study to analyze the association of three common SNPs of IL-17A rs2275913 and rs3748067 and IL-17F rs763780 gene polymorphisms with the risk of cervical cancer in a Chinese population.
The TT genotype and T allele of IL-17A rs3748067 and the CC genotype and C allele of IL-17F rs763780 carried a moderate risk of cervical cancer, when compared with the wild-type genotype.
In conclusion, our study suggests that the IL17A rs3748067</span> polymorphism is independently associated wit</span>h the risk of cervical cancer, and has a relationship with human papillomavirus infection with regard to the risk of cervical cancer.