Gene: APC ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1463038513
rs1463038513
APC
0.030 GeneticVariation BEFREE The I1307K mutation is common among Jews who have had colorectal neoplasms, but overall it was found to have little effect clinically in the current study group. 15959913

2005
dbSNP: rs1463038513
rs1463038513
APC
0.030 GeneticVariation BEFREE The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history. 9724771

1998
dbSNP: rs1463038513
rs1463038513
APC
0.030 GeneticVariation BEFREE These findings support a model where somatic instability of the (A)8 tract produced by the APC I1307K allele leads to increased APC gene inactivation and directly accounts for 42% of the colorectal neoplasms occurring in APC I1307K carriers. 9751605

1998
dbSNP: rs1801155
rs1801155
APC
0.030 GeneticVariation BEFREE The I1307K mutation is common among Jews who have had colorectal neoplasms, but overall it was found to have little effect clinically in the current study group. 15959913

2005
dbSNP: rs1801155
rs1801155
APC
0.030 GeneticVariation BEFREE The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history. 9724771

1998
dbSNP: rs1801155
rs1801155
APC
0.030 GeneticVariation BEFREE These findings support a model where somatic instability of the (A)8 tract produced by the APC I1307K allele leads to increased APC gene inactivation and directly accounts for 42% of the colorectal neoplasms occurring in APC I1307K carriers. 9751605

1998
dbSNP: rs1801166
rs1801166
APC
0.010 GeneticVariation BEFREE The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history. 9724771

1998
dbSNP: rs121913326
rs121913326
APC
T 0.700 GeneticVariation CLINVAR Comprehensive molecular characterization of human colon and rectal cancer. 22810696

2012
dbSNP: rs121913326
rs121913326
APC
T 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913326
rs121913326
APC
T 0.700 GeneticVariation CLINVAR Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer. 24861525

2015
dbSNP: rs121913326
rs121913326
APC
T 0.700 GeneticVariation CLINVAR APC mutations occur early during colorectal tumorigenesis. 1528264

1992
dbSNP: rs121913326
rs121913326
APC
T 0.700 GeneticVariation CLINVAR Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. 8187091

1994
dbSNP: rs121913327
rs121913327
APC
T 0.700 GeneticVariation CLINVAR Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. 1338904

1992
dbSNP: rs121913327
rs121913327
APC
T 0.700 GeneticVariation CLINVAR Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer. 24861525

2015
dbSNP: rs121913327
rs121913327
APC
T 0.700 GeneticVariation CLINVAR Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. 8187091

1994
dbSNP: rs121913327
rs121913327
APC
T 0.700 GeneticVariation CLINVAR APC mutations occur early during colorectal tumorigenesis. 1528264

1992
dbSNP: rs121913327
rs121913327
APC
T 0.700 GeneticVariation CLINVAR Comprehensive molecular characterization of human colon and rectal cancer. 22810696

2012
dbSNP: rs121913327
rs121913327
APC
T 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913327
rs121913327
APC
T 0.700 GeneticVariation CLINVAR A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas. 23204322

2012
dbSNP: rs121913327
rs121913327
APC
T 0.700 GeneticVariation CLINVAR "APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""." 10737795

2000
dbSNP: rs121913328
rs121913328
APC
T 0.700 GeneticVariation CLINVAR "APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""." 10737795

2000
dbSNP: rs121913328
rs121913328
APC
T 0.700 GeneticVariation CLINVAR Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. 1338904

1992
dbSNP: rs121913328
rs121913328
APC
T 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913328
rs121913328
APC
T 0.700 GeneticVariation CLINVAR Comprehensive molecular characterization of human colon and rectal cancer. 22810696

2012
dbSNP: rs121913328
rs121913328
APC
T 0.700 GeneticVariation CLINVAR APC mutations occur early during colorectal tumorigenesis. 1528264

1992